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Evaluation of Hyaluronic acid gel in the treatment of periodontal infrabony defects

Comparative evaluation of the regenerative efficacy of Hyaluronic acid gel combined with open flap debridement versus open flap debridement in the treatment of periodontal Infrabony defects: A Clinico-Radiographic Study

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2018/03/012334
Enrollment
30
Registered
2018-03-05
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- Patients with chronic periodontitis having at least two infrabony defects indicated for periodontal flap surgeries

Interventions

Intervention1: Hyaluronic acid gel in open flap debridement: The gel will be placed at the time of open flap debridement Control Intervention1: Not applicable: Not applicable

Sponsors

Dr Alefiya Mamajiwala
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Patients diagnosed with chronic periodontitis having at least two infrabony periodontal defects with pocket depth >=5mm. 2. Systemically healthy patients. 3. Patients should not have received antibiotic therapy or periodontal treatment within 6-month

Exclusion criteria

Exclusion criteria: Pregnant and lactating women. Smokers. Patients with any known allergies. Patients failing to observe the recommended oral hygiene measures.

Design outcomes

Primary

MeasureTime frame
(1) Probing Pocket Depth (PPD) (2) Clinical Attachment Level (CAL) (3) Gingival Recession (GR) (4) Plaque Index (PI) (Silness and Loe,1964) (5) Gingival Index (GI) (Loe and Silness,1963) Timepoint: Baseline, 3 months and 6 months

Secondary

MeasureTime frame
Radiographic assessment of the defect fillTimepoint: baseline, 3 months and 6 months postoperatively

Countries

India

Contacts

Public ContactDr Alefiya Mamajiwala

Professor and Guide

kunalks2001@yahoo.com

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 24, 2026