Health Condition 1: null- Patients undergoing elective surgery under general anaesthesia of expected duration less than 2 hours
Conditions
Interventions
Intervention1: DEXMEDETOMIDINE: Dexmedetomidine was diluted in 50 ml of 0.9% saline as 2µg/ml concentration and loaded in an infusion pump. After induction of general anaesthesia and intubation, all
Sponsors
Jawaharlal Institute of Postgraduate Medical Education Research
Eligibility
Inclusion criteria
Inclusion criteria: ASA 1 & 2 patients undergoing elective surgery of expected duration less than 2 hrs under general anaesthesia
Exclusion criteria
Exclusion criteria: Patients refusing consent, known history of psychiatric illness, chronic drug or alcohol abuse, known hypersensitivity to drugs used, family history of malignant hyperthermia, significant cardiopulmonary, hepatic or renal disease, pregnant and breast feeding women, hypertensive patients not on any treatment or those treated with alpha or beta blockers and patients on concurrent sedative medications
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Psychomotor function was assessed by Trieger dot test (TDT) and Digit symbol substitution test (DSST).Timepoint: Both the tests were done pre-operatively (baseline), 30 minutes, 60 minutes, 90 minutes and 120 minutes after extubation. | — |
Secondary
| Measure | Time frame |
|---|---|
| Total opioid requirementTimepoint: Fentanyl 1 µg/kg was supplemented whenever there was increase in patients heart rate or blood pressure by 30% from baseline in both the groups during surgery | — |
Countries
India
Contacts
Public ContactDr Ayyappan C
JIPMER
Outcome results
None listed