FindTrial
Sign In

Effect of Acute Decompensation(complication of liver disease) in Patients with liver disease

Impact of Acute Decompensation in Patients of Cirrhosis With or Without Prior Decompensation - A Prospective Observational Study.

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2018/03/012321
Enrollment
80
Registered
2018-03-05
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- Acute Decompensation in Cirrhosis Health Condition 2: K746- Other and unspecified cirrhosis ofliver

Interventions

None listed

Sponsors

Institute of liver and Biliary Sciences
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1.Cirrhosis with decompensation in a period of 3 months in form of ascites, jaundice, HepaticEncephalopathy, Acute Variceal bleed irrespective of prior decompensation. 2.Age 18-70 years 3.Valid consent

Exclusion criteria

Exclusion criteria: 1.HepatoCellular Carcinoma 2.Admitted and survival less than 48 hrs 3.Pregnant 4.Acute Liver Failure 5.Post Transplant

Design outcomes

Primary

MeasureTime frame
Spontaneous recovery, liver transplant or death in 90 daysTimepoint: 90 days—

Secondary

MeasureTime frame
Cause of acute decompensation.Timepoint: 90 days;Causes of deathTimepoint: 90 days;Improvement in severity assessment Indices (MELD, CTP, SOFA, APACHE II and CLIF SOFA scores)Timepoint: 90 days;Profile of patient undergone transplantTimepoint: 90 days;Sepsis, SIRS and infectionTimepoint: 90 days;Severity and duration of prior as well as present decompensationTimepoint: 90 days—

Countries

India

Contacts

Public ContactDr Ashok Kumar Choudhary

Institute of liver and Biliary Sciences

doctor.ashokchoudhury@gmail.com01146300000

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026