To study effects of coconut oil and laser in leukoplakia

Pre and post treatment expression of CD163 in OSMF and role of CD68, CD163 and STAT1 as potential biomarkers in OPMD

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2018/03/012299

Enrollment

Registered

2018-03-05

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- Leukoplakia

Interventions

Intervention1: Group A: coconut oil: Oil pulling using 10ml coconut oil thrice daily for 2 months Control Intervention1: Group B: Laser treatment: Treatment of lesion using diode laser at 980 nm Cont

Eligibility

Inclusion criteria

Inclusion criteria: Clinically and histopathologically proven cases of Leukoplakia Positive habit history of tobacco, smoking, betel quid, alcohol

Exclusion criteria

Exclusion criteria: Those who are not willing to participate Patient already undertaking some form of treatment Patient with severe systemic disease

Design outcomes

Primary

Measure	Time frame
Evaluation of extent of lesion, site , surface texture, staging between groups and within groupTimepoint: At time of first visit every month till a period of nine month	—

Secondary

Measure	Time frame
Reporting of malignant transformation over period of 9 monthsTimepoint: Individuals were assessed every 4 weeks for 9 months. In case of suspicious lesion biopsy was done	—

Countries

India

Contacts

Public ContactDr Sunita Gupta

Maulana Azad Institute of Dental Sciences

drsunitagupta@yahoo.com9654700955

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026