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To measure how much of egg protein is taken up by the body for its use

Measurement of protein digestibility using intrinsically labeled egg and poultry meat in humans

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2018/03/012265
Enrollment
18
Registered
2018-03-01
Start date
Unknown
Completion date
Unknown
Last updated
2024-10-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Intervention1: Nil: Nil Control Intervention1: Nil: Nil

Sponsors

DBT Wellcome Trust Margadarshi Fund
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: BMI between18.5 to 25 Kg/m²

Exclusion criteria

Exclusion criteria: History of smoking or taking other leisure drugs Consumption of alcohol in the previous 24 hours History of antibiotic usage 4 weeks prior to the study On iron supplementation therapy (3 months) On medication such as NSAID’s, proton pump inhibitors or H2 blockers 2 days prior to and on the study day Participation in any nutritional study in the last 6 months History of food allergy, specifically to egg or meat protein Diagnosed with chronic medical or surgical illness

Design outcomes

Primary

MeasureTime frame
Protein Digestibility measures of intrinsically 2H labeled egg and poultry meat protein in healthy adult humans using the dual tracer approachTimepoint: Blood sampling time points for digestibility measurement include half hourly once from 5th hour to 8th hour

Secondary

MeasureTime frame
Comparison between the mean digestibilities of the two methods of egg protein processed test meal fed to the subjectsTimepoint: Average of 7 blood time point enrichment values will be taken for digestibility calculation and compared between two methods of processing;Determination of the functional status of the intestine using plasma kynurenine and KT ratio to rule of any effect of poor intestinal health on the digestibilityTimepoint: Basal (1 time point) plasma sample will be used for analysis and determination of plasma kynurenine and KT ratio;Determine the influence of tea polyphenol on whole egg individual true ileal digestibilityTimepoint: Average of 7 time points plasma enrichment values will be used for digestibility calculation and a comparison between true ileal IAA digestibility of egg with and without tea polyphenol will be made

Countries

India

Contacts

Public ContactNirupama Shivakumar

St. Johns National Academy of Health Sciences

nirupama.s@sjri.res.in9900070008

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Mar 5, 2026