Health Condition 1: null- Children suffering from Benign Epilepsy with centro-temporal spikes ( BECTS)
Conditions
Interventions
Intervention1: Treatment with antiepileptic drug Valproate: Valproate would be started to patients randomized to treatment group
Control Intervention1: No treatment: Patients randomized to no treatmen
Sponsors
Bharati Vidyapeeth Medical College Pune
Eligibility
Inclusion criteria
Inclusion criteria: 1. Onset of seizures after the age of 3 years 2. History of at least one typical seizure 3. Normal neurological and development history 4.Clinical and EEG criteria suggestive of BECTS according to ILAE criteria 5. No other seizure type
Exclusion criteria
Exclusion criteria: 1. Prior neurological deficits 2. Pre-existing psychiatric conditions 3. Symptomatic etiology 4. 3 or more seizures in last 3 months 5. Already on anti-epileptics for more than a week
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To compare the changes in cognition ( IQ), language, behavior and academic achievement of children with newly diagnosed BECTS, between the no treatment group versus the Treatment group; from baseline to follow up over 2 years.Timepoint: 3 monthly till 2 years | — |
Secondary
| Measure | Time frame |
|---|---|
| i) To study the clinical and the EEG profile in these children at baseline and further till 2 years ii) To compare the seizure recurrence rates between the two groups iii) To monitor for any adverse effects related to the drug (in treatment group). Timepoint: 3 monthly till 2 years | — |
Countries
India, United Arab Emirates
Contacts
Public ContactDr Kavita Srivastava
Bharati Vidyapeeth Medical College, Pune
Outcome results
None listed