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A study to compare the effect of blood component and dextrose injection in patients of chronic severe plantar fasciitis

A randomized control trial to compare the effect of platelet rich plasma and dextrose prolotherapy in patients of chronic severe plantar fasciitis

Status
Active, not recruiting
Phases
Phase 2Phase 3
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2018/02/012220
Enrollment
60
Registered
2018-02-28
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- Plantar fasciitis

Interventions

Intervention1: 15% dextrose solution: 1.5 mL of 25% dextrose is mixed with 1ml of 2% lignocaine taken in a 5mL syringe to make 2.5ml of 15% dextrose solution Control Intervention1: Platelet rich plasm

Sponsors

Krishna B
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Patient diagnosed with unilateral or bilateral plantar fasciitis having no improvement with conservative management for >= 3 weeks. 2.Physical examination revealing maximum tenderness at the attachment of plantar fascia on the medial tubercle of the calcaneus. 3.Ultrasound examination showing plantar fascia thickness >=4 mm or difference in plantar fascia thickness >=1 mm in symptomatic heel in comparison to asymptomatic heel at inferior border of the calcaneus. 4.In bilateral cases, foot with more clinical severity is taken into the study

Exclusion criteria

Exclusion criteria: 1.Received local steroid injection within 6 months 2. NSAID use 7 days prior to randomization 3. History of anaemia or bleeding disorders 4. Previous surgery for plantar fasciitis 5. Achilles tendon pathology 6.Diagnosed case of local malignancy 7.Diagnosed case of rheumatological diseases 8.Uncontrolled diabetes mellitus 9.Patients on anticoagulation therapy 10. Diagnosis of vascular insufficiency or neuropathy related heel pain (radiculopathy, tarsal tunnel syndrome) and other causes of heel pain 11. Any local trauma or infection. 12.Not willing to participate in study

Design outcomes

Primary

MeasureTime frame
Change in sonographic appearance of the plantar fascia, with respect to thickness and presence or absence of hypoechogenic fociTimepoint: 0 weeks , 4 weeks, 8 weeks

Secondary

MeasureTime frame
Change in functional outcome assessed by Foot Function IndexTimepoint: 0 weeks, 4 weeks, 8 weeks;Change in symptom severity assessed by Foot Function IndexTimepoint: 0 weeks, 4 weeks, 8weeks

Countries

India

Contacts

Public ContactKrishna B

AIIMS

gitahanda@gmail.com09818694060

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026