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A comparative study in Head and Neck cancer patients of the two methods of giving oxygen to patient during operation namely THRIVE and NODEST for maintaining the sufficient blood oxygen level during throat extermination and biopsy with microscope

A Randomised Controlled Trial to Compare THRIVE versus NODESAT Techniques of Oxygenation to Prolong Safe Apnoea Time During Microlaryngoscopy In Head And Neck Cancer Patients

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2018/02/012207
Enrollment
60
Registered
2018-02-28
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: C148- Malignant neoplasm of overlappingsites of lip, oral cavity and pharynx

Interventions

Intervention1: THRIVE (Trans-Nasal Humidified Rapid Insufflation Ventilator Exchange)method of oxygentaion: newer method of oxygenation provide oxygen at 70 L/min at optimal temperature and humidity C

Sponsors

Tata Memorial Hospital
Lead Sponsor
Not Any
Collaborator

Eligibility

Inclusion criteria

Inclusion criteria: 1.Adult patients (Age >=18 years) undergoing Micro-laryngoscopy procedures 2. ASA score 1 and 2 3.Procedure expected to last for > 15 minutes. 4.Patients having patent airway

Exclusion criteria

Exclusion criteria: 1.Age less than 18 years 2.Patients in stridor 3.Patients having pre-existing respiratory comorbidities (COPD, Asthma) 4.Emergency procedure

Design outcomes

Primary

MeasureTime frame
To find out feasibility of THRIVE as a method apnoeic oxygenation during MLscopy guided biopsyTimepoint: at baseline, preoxygenation, o min after giving muscle relaxant and then at every every minute till 45 minute after giving muscle relaxant—

Secondary

MeasureTime frame
to calculate the time frame during which oxygenation is maintained using the techniques of either THRIVE or NO DESAT.Timepoint: Single time point during surgery—

Countries

India

Contacts

Public ContactDrNilashree Das

Tata Memorial Center

sheila150@hotmail.com9820156070

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026