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A clinical trial intended to study the effect of drug dexmedetomidine in preventing agitation in adults after surgery under general anaesthesia

Dexmedetomidine infusion for prevention of emergence agitation after nasal surgery

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2018/02/012197
Enrollment
100
Registered
2018-02-28
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- Health patients without any comorbidities

Interventions

Intervention1: Dexmedetomidine: Dexmedetomidine as an intravenous infusion at the rate of 0.4mcg/kg/hr from the beginning of induction of general anaesthesia till extubation Control Intervention1: Pla

Sponsors

Tejesh CA
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: American Society of Anaesthesiologists (ASA)grade 1 and 2 Patients undergoing nasal surgery under general anaesthesia and requiring nasal packing after surgery

Exclusion criteria

Exclusion criteria: Known or suspected allergy to α2 adrenergic agonists. Use of monoamine oxidase inhibitors, adrenergic blocking agents or clonidine. Uncontrolled hypertension and Diabetes mellitus. Heart block greater than first degree. Cognitive impairment. Chronic use of antipsychotic medications. Kidney or liver disease. Body Mass index >=30kg/m² Pregnancy

Design outcomes

Primary

MeasureTime frame
Emergence agitation assessed by Ricker sedation-agitation scaleTimepoint: Emergence agitation assessed by Ricker sedation-agitation scale immediately after extubation of the patient

Secondary

MeasureTime frame
1.Time to verbal response and extubation 2.Introperative analgesic requirement 3.Duration of PACU stayTimepoint: 1.After patient awakening from anaesthesia 2.At the end of Intraoperative period 3.At the time of discharge from recovery room

Countries

India

Contacts

Public ContactTejesh CA

MS Ramaiah Medical College

drtejeshca@yahoo.com

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026