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Clinical efficacy of Chandramrita Rasa on Bronchial Asthma

Pre-clinical Safety, Efficacy of Chandramrita Rasa and its clinical efficacy in the management of Tamaka Shwasa (Bronchial asthma)

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2018/02/012179
Enrollment
60
Registered
2018-02-27
Start date
Unknown
Completion date
Unknown
Last updated
2022-11-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- Patients having classical signs and symptoms of Tamaka Shwasa(Bronchial Asthma)

Interventions

Intervention1: Chandramrita Rasa: 375 mg twice with Honey orally for 28 Days Control Intervention1: Not Applicable: Not Applicable

Sponsors

Institute for Post Graduate Teaching and Research in Ayurveda
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1.Both the sexes having age between 18 years to 60 years 2.Mild persistent cases of Bronchial Asthma with day time symptoms 3-6/week and nocturnal symptoms with 3-4/month. 3.Moderate persistence cases with daytime symptoms daily and nocturnal symptoms with one or more than one week but not more than 2 weeks.

Exclusion criteria

Exclusion criteria: 1.Age more than 60 years and below 18 years. 2.Mild intermittent, Moderated persistent, severe persistent to severe Asthma. 3.Dyspnoea resulting from other diseases like left ventricular failure, COPD (like Chronic Bronchitis, Emphysema), upper respiratory tract obstruction, bronchiectasis, cases of tuberculosis, interstitial lung disease/occupational lung disease, tropical pulmonary eosinophilia & allergic bronchopulmonary aspergillosis etc. 4.Patients having anaemia, pneumonia, tuberculosis, lung cancer, lung abscess and other such complicated conditions. 5.Patients having diabetes, hypertension, Chronic and Acute renal failure etc. conditions in which urination is markedly diminished or excessive were excluded. 6.HIV positive cases. 7.Pregnant/lactating mother. 8.Patients who need Salbutamol inhaler daily. 9.Patients having classical symptoms of Maha, Urdha, Chhinna and Kshudra Shwasa.

Design outcomes

Primary

MeasureTime frame
It is expected that the trial drugs will exert a significant action on Signs and Symptoms of Tamaka Shwasa. Improvement in AEC and other haematological (TLC, DLC, Hb, AEC), Peak Expiratory Flow Rate and Breath Holding Time.Timepoint: 18 Months

Secondary

MeasureTime frame
By providing better effect on Tamaka Shwasa, the drug will effect psychosomatic level of the enrolled patients, enhance quality of life and will contribute in reducing disability adjusted life years. Overall improvement in the disease condition, Quality of Life of the diseased. Based on the observations, the trial drug may be recommended to be added into the Essential Drugs List of Ministry of AYUSH, New DelhiTimepoint: 18 Months of Trial

Countries

India

Contacts

Public ContactProf BJ Patgiri

Institute for Post Graduate Teaching and Research in Ayurveda Jamnagar

patgiri124@gmail.com9426947438

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026