Health Condition 1: null- SUBCLINICAL HYPOTHYROIDISM
Conditions
Interventions
Intervention1: the eligible patients will be treated with Vit-D3 sachets 60 000 once a week for 8 weeks followed by once a month for 4months.: Each eligible patient will be served as own controls.
Con
Sponsors
AIIMS Bhubaneswar
Eligibility
Inclusion criteria
Inclusion criteria: Patients with either sex aged more than 18yrs with positive TPO antibody with subclinical hypothyroidism (normal FT4 & FT3 with TSH Patient with vit d deficiency
Exclusion criteria
Exclusion criteria: Patients with hypothyroidism of low ft4& ft3 with TSH > 10 MIU/ml Patients with subclinical hypothyroidism with Infertility Planning for conceive Dyslipidemia Psychiatric disorder Severe cardio vascular disease Liver disease Renal disease Drugs (Hormones, antiepileptic, AT, & Glucocorticoids)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To evaluate the effect of Vit-D supplementation and its effect on improvement of thyroid antibody titer and thyroid hormone profile in patients with AITD with subclinical hypothyroidism.Anti TPO antibody titer of 25% decrease from the base line after Vit d therapy will be taken as significant respond to the treatment.Timepoint: one yrs | — |
Secondary
| Measure | Time frame |
|---|---|
| To evaluate whether Vit-D supplementation should be recommended in those patients.Timepoint: one yrs | — |
Countries
India
Contacts
Public ContactKishore Kumar Behera
AIIMS Bhubaneswar
Outcome results
None listed