Health Condition 1: C71- Malignant neoplasm of brain Health Condition 2: null- supra tentorial tumour resction under general anaesthesia
Conditions
Interventions
None listed
Sponsors
Nimhans
Eligibility
Inclusion criteria
Inclusion criteria: elective supratentorial tumour resection under GA electively
Exclusion criteria
Exclusion criteria: Age less than 18yrs Emergency surgery Patients on beta blockers ,calcium channel blockers Patients with autonomic dysfunction, thyroid dysfunction Patients with peripheral vascular disease Patients with HB less than 11g/dl Patient requiring major blood transfusion more than 50% blood volume. BMI more than 35 Patients with significant organ system dysfunction Intraoperative hemodynamic instability ;defined as a fall in blood pressure by 30% of baseline Patients requiring inotropic and vasopressor infusion
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Evaluating the changes in SPI and ANI with changes in HR and MAP at predefined time pointsTimepoint: asessed at end of data aquisiotion period of 14-18 months | — |
Secondary
| Measure | Time frame |
|---|---|
| Evaluating the changes in SPI and ANI with changes in HR and MAP at predefined stimulus timesTimepoint: at end of study;Evaluating the numerical pain score at the end of one hour following the completion of surgery and evaluating the correlation of the numerical pain score with ANI and SPI at one hour post surgery.Timepoint: end of study;To evaluate the change in SPI and ANI independently at all these time points of surgical stimulation.Timepoint: at end of study | — |
Countries
India
Contacts
Public ContactPrashanth A Menon
NIMHANS Bangalore
Outcome results
None listed