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Comparison of two drugs given in spinal anaesthesia for postoperative pain relief in patients undergoing lower limb orthopaedic surgery.

Comparison of post operative analgesic effects of intrathecal nalbuphine and intrathecal clonidine in patients undergoing elective lower limb orthopaedic surgeries : a prospective randomized double blind study.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2018/02/012157
Enrollment
99
Registered
2018-02-26
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- fracture femur

Interventions

Intervention1: 3. Group C: - 2.6 ml of 0.5% hyperbaric bupivacaine and 0.4 ml of 60 μg clonidine.: the patients were randomly allocated into nalbuphine group (Group N), Clonidine group (Group C) o

Sponsors

Shri Dharmasthala Manjunatheshwara College of Medical Sciences and Hospital Dharwad
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Aged between 18 and 60 years ASA Physical status 1, 2 and 3 Patients undergoing elective lower limb long bone orthopaedic surgery under sub arachnoid block.

Exclusion criteria

Exclusion criteria: 1. Patients with ischemic heart disease, neurological or psychiatric disorders, renal or hepatic insufficiency. 2. Pregnant or lactating women. 3. Obese as defined by a BMI of more than 30 kg/m2. 4. Patients on α antagonists. 5. Patients allergic to the medications being used. 6. CNS and local infections. 7. Spine deformities, raised intracranial pressure and progressive neurological disorders. 8. Those parents who refuse consent

Design outcomes

Primary

MeasureTime frame
Pain free Interval After Surgery No Of rescue Pain Medication needed in first 24 hours of surgery. Average Visual Analogue Scale for Pain during assessment period.Timepoint: First 24 hours after surgery.

Secondary

MeasureTime frame
duration of analgesia pain scoreTimepoint: 24 hours

Countries

India

Contacts

Public ContactDr Krishna Sagar SR

Shri Dharmasthala Manjunatheshwara College of Medical Sciences and Hospital, Dharwad

kakkodravi@yahoo.co.in0836-2477755

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026