Comparative study between intrathecal magnesium sulphate and intrathecal fentanyl as an adjuvant to Bupivacaine in spinal anesthesia for patients undergoing lower limb orthopedic surgery

Status

Recruiting

Phases

Phase 3Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2018/02/012149

Enrollment

100

Registered

2018-02-26

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- 1.AMERICAN SOCIATY OF ANESTHESIOLOGIST GRADE 1 & 2 2.Age group 18-60 years of either sex 3.Patients giving valid informed consent

Interventions

Intervention1: Intrathecal bupivacaine and intrathecal fentanyl: 3ml (0.5%)bupivacaine 0.5 ml (25mcg)fentanyl Control Intervention1: Intrathecal bupivacaine and intrathecal magnesium sulphate: 3ml (0.

Eligibility

Inclusion criteria

Inclusion criteria: 1.ASA grade 1 and 2 patients 2.Age group 18-60 years of either sex 3.Patients giving valid informed consent 4.Height 150-180cm and those undering lower limb orthopedic surgery

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Post-operative analgesic effectTimepoint: Post-operative analgesic effect	—

Secondary

Measure	Time frame
Nausea,Vomitting,Hypotension,Bradycardia,Respiratory depression,Pruritus,Urinary retention,maximum sedation scoreTimepoint: 1 min,5 min,10 min,15 min,20 min,25 min, 30 min,35 min,40 min,45 min, 50 min, 55 min, 60 min	—

Countries

India

Contacts

Public ContactDR AJIT GUPTA

INDIRA GANDHI INSTITUTE OF MEDICAL SCIENCES,PATNA

ajpta_igims@yahoo.co.uk9473191810

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026