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To study the difference between pre-decided dose and calculated dose as per height of patient for the drug 0.5% bupivacaine injected around the spinal cord for anaesthesia in patients for casearean delivery

Comparison of height adjusted dose versus fixed dose of 0.5% hyperbaric bupivacaine in spinal anaesthesia for caesarean delivery

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2018/02/012111
Enrollment
110
Registered
2018-02-23
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- Pregnant patients for casearean section under spinal anaesthesia

Interventions

Intervention1: Height adjusted dose: Patients in this group will receive height adjusted dose (0.06 mg/ cm height) of 0.5% bupivacaine heavywith 10µg fentanyl in spinal anaesthesia Control Interventi

Sponsors

Deen Dayal Upadhyay Hospital
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: American Society of Anesthesiologists physical status I or II women with term pregnancy ( > 37 weeks gestation), with singleton pregnancy, with Height between 140 cm to 170 cm (both values inclusive) and Weight between 40 kg to 90 kg (both values inclusive)

Exclusion criteria

Exclusion criteria: 1.Patient refusal 2.Pre-existing or pregnancy induced hypertension 3.Diabetes Mellitus, cardiovascular or cerebrovascular disease 4.Spine deformities or history of spine surgery 5.Foetal abnormality, fetal distress, complicated pregnancy 6.Allergy to any study medication 7.Absolute or relative contraindication to spinal anaesthesia

Design outcomes

Primary

MeasureTime frame
To compare the incidence of hypotension, in parturients receiving height adjusted dose and fixed dose of 0.5% hyperbaric bupivacaine under spinal anaesthesia for caesarean deliveryTimepoint: injection of spinal anaesthetic drug till the end of surgery—

Secondary

MeasureTime frame
Incidence of bradycardia, nausea, vomitingTimepoint: injection of spinal anaesthetic drug till complete motor (muscle power)recovery;Motor block characteristics Timepoint: injection of spinal anaesthetic drug till complete motor (muscle power)recovery;Neonatal outcome (Apgar score)Timepoint: Apgar score at 1 minute and 5 minute post delivery of baby;Sensory block characteristicsTimepoint: injection of spinal anaesthetic drug till regression of sensory block to S2 dermatome.;Total dose of Injection mephentermine used to treat hypotensionTimepoint: injection of spinal anaesthetic drug till complete motor (muscle power)recovery—

Countries

India

Contacts

Public ContactDr Satishkumar Mandve

Deen Dayal Upadhyay Hospital, Govt. of NCT of Delhi

ajayannu@gmail.com9718990114

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026