Role of Yoga on Obstructive Sleep Apnea (OSA)

Effect of yoga on health-related status and cardiovascular risk factors among obstructive sleep apnoea patients: A Multi-Centric Randomized Controlled Trial

Status

Active, not recruiting

Phases

Phase 2Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2018/02/012105

Enrollment

120

Registered

2018-02-23

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- OBSTRUCTIVE SLEEP APNEA

Interventions

Intervention1: Yoga with standard of care group: The intervention group will be taught yoga practices by institutionally trained yoga therapist (as per the protocol enclosed) at CIMR, AIIMS and Dayana

Eligibility

Inclusion criteria

Inclusion criteria: 1. Patients of all genders and age between 18-70 years. 2. Patients from Delhi NCR for study settings in Delhi. 3. Medical history which is compatible with OSA and AHI more than 15 per hour. 4. Availability of time to include physical activity in their daily routine and to come for the contact classes and investigations as per the protocol. 5. Not been engaged in regular yoga practice or any other alternative medicine for the same desired effect.

Exclusion criteria

Exclusion criteria: 1. Patientâ??s refusal for Polysomnography. 2. Patients on CPAP. 3. Patients with a well-documented chronic history of congestive heart failure, chronic renal failure or chronic liver failure. 4. Patients having very severe hypoxemia (oxygen saturation 10% of recording time). 5. Pregnancy 6. Morbid obesity, Hypothyroidism 7. Patients underwent any metabolic surgery 8. Recent trauma to upper respiratory tract 9. Patients on systemic corticosteroid treatment 10. Inability to perform yoga exercises due to orthopaedic or musculoskeletal problems. 11. Patients currently participating in any other clinical trials in the same hospital or any other sites.

Design outcomes

Primary

Measure	Time frame
1. Apnoea hypopnea index 2. Oxygen desaturation index (ODI) 3. Heart Rate Variability (HRV)Timepoint: Baseline, at 2 weeks,at 3 months, at 6 months, and at 12 months from baseline	—

Secondary

Measure	Time frame
General metabolic parametersTimepoint: Baseline, at 2 weeks,at 3 months, at 6 months, and at 12 months from baseline;Hamiltonâ??s Depression Questionnaire (HAM-D)Timepoint: Baseline, at 2 weeks,at 3 months, at 6 months, and at 12 months from baseline;Neuropsychological Evaluation Screening Tool (NEST) and Hindi Mental Status Examination (HMSE)Timepoint: Baseline, at 2 weeks,at 3 months, at 6 months, and at 12 months from baseline;Stress and Inflammatory biomarkersTimepoint: Baseline,at 3 months, at 6 months, and at 12 months from baseline;The Hamilton Anxiety Rating Scale (HAM-A)Timepoint: Baseline, at 2 weeks,at 3 months, at 6 months, and at 12 months from baseline;The Pittsburgh Sleep Quality Index (PSQI)Timepoint: Baseline, at 2 weeks,at 3 months, at 6 months, and at 12 months from baseline;Wechsler Memory Scale- III (WMS III) Indian EditionTimepoint: Baseline, at 2 weeks,at 3 months, at 6 months, and at 12 months from baseline;WHO QoL BREF questionnaireTimepoint: Baseline, at 2 weeks,at 3 months, at 6 months, and at 12 months from baseline	—

Measure

Time frame

General metabolic parametersTimepoint: Baseline, at 2 weeks,at 3 months, at 6 months, and at 12 months from baseline;Hamiltonâ??s Depression Questionnaire (HAM-D)Timepoint: Baseline, at 2 weeks,at 3 months, at 6 months, and at 12 months from baseline;Neuropsychological Evaluation Screening Tool (NEST) and Hindi Mental Status Examination (HMSE)Timepoint: Baseline, at 2 weeks,at 3 months, at 6 months, and at 12 months from baseline;Stress and Inflammatory biomarkersTimepoint: Baseline,at 3 months, at 6 months, and at 12 months from baseline;The Hamilton Anxiety Rating Scale (HAM-A)Timepoint: Baseline, at 2 weeks,at 3 months, at 6 months, and at 12 months from baseline;The Pittsburgh Sleep Quality Index (PSQI)Timepoint: Baseline, at 2 weeks,at 3 months, at 6 months, and at 12 months from baseline;Wechsler Memory Scale- III (WMS III) Indian EditionTimepoint: Baseline, at 2 weeks,at 3 months, at 6 months, and at 12 months from baseline;WHO QoL BREF questionnaireTimepoint: Baseline, at 2 weeks,at 3 months, at 6 months, and at 12 months from baseline

—

Countries

India

Contacts

Public ContactGautam Sharma

Centre of Integrative Medicine and Research (CIMR)

drsharmagautam@gmail.com

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026