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Treatment of fungal infection of nail with LASER and its comparison with oral antifungal Itraconazole

A comparative study of Fractional CO2 Laser with 1% Terbinafine cream versus Itraconazole in the management of Onychomycosis

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2018/02/012060
Enrollment
100
Registered
2018-02-21
Start date
Unknown
Completion date
Unknown
Last updated
2022-10-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- Onychomycosis Health Condition 2: L608- Other nail disorders

Interventions

Intervention1: Fractional CO2 Laser and topical Terbinafine cream: 50 Onychomycosis patients, Fractional CO2 Laser would be done at monthly intervals for four months in patients with Onychomycosis. Th

Sponsors

Command hospital Air Force Bangalore
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1.Males and females over the age of 18 years 2.Patient with one or more toenail and/or fingernail fungal infections of the following types: distal subungual onychomycosis, proximal subungual onychomycosis, superficial white or black onychomycosis, mixed patterns or total dystrophic type onychomycosis. 3.Confirm diagnosis using fungal culture and direct microscopy.

Exclusion criteria

Exclusion criteria: 1.Fungal culture negative or no evidence on direct microscopy. 2.Those patients who used systemic or topical antifungal in the past three months. 3.Conditions like bacterial infections, subungual hematoma, associated nail disorders which produce changes in the nail plate like psoriasis, atopic dermatitis, lichen planus. 4.Pregnant women.

Design outcomes

Primary

MeasureTime frame
Reduction in Onychomycosis Severity Index or complete clearanceTimepoint: 6 MONTHS

Secondary

MeasureTime frame
Reduction in Onychomycosis Severity Index or complete clearanceTimepoint: AT 3, 4 AND 5 MONTHS

Countries

India

Contacts

Public ContactS Radhakrishnan

Command hospital Air Force

eeshaan.ranjan@gmail.com9720639323

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026