Effect of a mouthwash containing hyaluronidase on gum disease

Efficacy of a new Hyaluronic Acid based mouth rinse on dental plaque, gingivitis, extrinsic stains and calculus - a randomized clinical trial; a randomized controlled trial

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2018/02/012054

Enrollment

Registered

2018-02-21

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Intervention1: Hyaluronidase based mouthrinse: 15 ml of mouthrinse is swished around the mouth twice daily for one minute and spat out.This is done for 21 days. Control Intervention1: Chlorhexidine ba

Eligibility

Inclusion criteria

Inclusion criteria: 1. Between 18 to 25 years of age 2. Full set of sound dentition 3. PD Probing depth-Periodontal pocket 4. No orthodontic treatment in progress (including removable maintenance appliances) 5. Patients had to exhibit a minimum of 30% of bleeding on probing

Exclusion criteria

Exclusion criteria: 1. Previous 3 months periodontal treatment 2. Previous 1 month mouthrinses or local or general medication 3. Any condition related with allergy or sensitivity with the mouthrinses ingredients 4. Systemic and chronic diseases in progress

Design outcomes

Primary

Measure	Time frame
GingivitisTimepoint: 0 and 21 days	—

Secondary

Measure	Time frame
CalculusTimepoint: 0 and 21 days;Extrinsic teeth stainingTimepoint: 0 and 21 days;PlaqueTimepoint: 0 and 21 days	—

Countries

India

Contacts

Public ContactPrabu Duraiswamy

Postgraduate student

bharatvenkat92@gmail.com

Outcome results