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Trial to compare efficiency of a drug used to reduce blood loss in surgical procedures when given through veins before start of surgery versus when sprayed at the site of surgery.

Comparison of efficacy of intravenous versus topical tranexamic acid in total hip replacement

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2018/02/012030
Enrollment
75
Registered
2018-02-21
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- Total blood loss in total hip replacement

Interventions

Intervention1: Tranexamic acid will be administered in the study to evaluate its effect on decreasing total blood loss in total hip replacement when given through two different routes of administratio

Sponsors

Sunhsine hospitals
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Informed consent Those undergoing primary,unilateral hip replacement.

Exclusion criteria

Exclusion criteria: 1.History of reported allergy to tranexamic acid 2.Patients who had been administered anticoagulants and antiplatelet drugs preoperatively 3.Ischemic heart disease 4.chronic renal failure 5.A history of hip surgery 6.Thromboembolic episodes 7.Rheumatoid arthritis

Design outcomes

Primary

MeasureTime frame
Total blood loss Change in hematocrit levels at 2nd postoperative day Operation timeTimepoint: Total blood loss Change in hematocrit levels at 2nd postoperative day Operation time—

Secondary

MeasureTime frame
1.Transfusion rates 2.Deep venous thrombosis 3.Pulmonary embolisation ratesTimepoint: 1.5th post operative day 2.90 days 3.90 days—

Countries

India

Contacts

Public Contactvishwanath mahadevuni

sunshine hospitals

mahadevuni.vishwanath206@gmail.com9493317314

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026