Health Condition 1: null- ASA physicalstatus I &II posted for elective lower abdominal surgeries
Conditions
Interventions
Intervention1: epidural dexmedetomidine 1mcg/kg: patients in Group D- Dexmedetomidine group, will receive Dexmedetomidine (1.0mcgg / kg) constituted to 1ml with normal saline +7ml of 0.125% bupivacai
Sponsors
none
Eligibility
Inclusion criteria
Inclusion criteria: 1.patients of ASA physical status I-II 2.Aged between 18 to 65 years of either sex.
Exclusion criteria
Exclusion criteria: 1.Contraindications to regional anesthesia: 2.Raised ICT 3.Patients refusal 4.local site infection 5.coagulation abnormalities, 6.allergy to local anaesthetics (amide group), 7.previous spine surgeries / spine deformities 8.Morbidly obese patients 9.neurologic, psychiatric disease, severe renal or hepatic derangement 10.Patients with history of drug abuse. 11.History of allergy or contraindications to either Dexmedetomidine or buprenorphine . 12.Concomitant use of medications which may exaggerate the heart rate response of Dexmedetomidine including digoxin or β-adrenergic antagonists. � Patients who are pregnant and lactating mothers
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| analgesic effectivenessTimepoint: analgesic effectiveness | — |
Secondary
| Measure | Time frame |
|---|---|
| sedation,nausea, vomiting, pruritis, other side effects and hemodynamicsTimepoint: heart rate, blood pressure and respiratory rate recorded every 5min for first 30 min, every 10min for next 30min, every 15min next 60min and at every 30mins for next 4 hours. | — |
Countries
India
Contacts
Public ContactDr Navya C N
Outcome results
None listed