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A Scientific trial to compare two drugs-dexmeditomidine and clonidine in nasal suregery for lowering blood pressure intra operatively.

A Comparative Evaluation of Intravenous Dexmedetomidine or Clonidine Premedication on Controlled Hypotension for Functional Endoscopic Sinus Surgery - DOCHFESS

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2018/02/011955
Enrollment
60
Registered
2018-02-19
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: - Health Condition 2: null- ASA I,II

Interventions

Intervention1: Dexmeditomidine Clonidine: Clonidine and dexmedetomidine cause a decrease in heart rate and blood pressure thereby providing controlled hypotension,enabling a bloodless surgical field

Sponsors

Government of Gujarat
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: ASA grade I and II Age between 18 to 50 Both sexes

Exclusion criteria

Exclusion criteria: Patient refusal. Known hypersensitivity or contraindication to clonidine, dexmedetomidine, nitro-glycerine, fentanyl Pregnancy or lactating mothers History of hepatic, renal or cardiopulmonary diseases History of significant neurological, psychiatric, or neuromuscular disorders Alcoholism, diabetes, hyper or hypothyroidism Patients on calcium channel blockers Bleeding diathesis

Design outcomes

Primary

MeasureTime frame
Intra operative controlled hypotensionTimepoint: Intra operative—

Secondary

MeasureTime frame
Intra operative blood loss Surgeons satisfaction score Peri operative complicationsTimepoint: Pre operatively Intra operative Post operative—

Countries

India

Contacts

Public ContactDr Smita Engineer

BJ Medical College

janu234@gmail.com9535619079

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026