Health Condition 1: null- Lipid profile,free androgen index and basal insulin of non-obese PCOS women Health Condition 2: E888- Other specified metabolic disorders
Conditions
Interventions
Intervention1: DRONIS 20 and MINNESE 15: I) Ethinyl estradiol (20mcg) and Drosperinone (3mg) for 12months with cyclical regime of 24 days
II) Ethinyl estradiol (15mcg) and Gestodene(60mcg) for 12mont
Sponsors
Chittaranjan Seva Sadan and Sishu Sadan College of Obstetrics Gynaecology and Child Health
Eligibility
Inclusion criteria
Inclusion criteria: Diagnosis of PCOS according to Rotterdam criteria with Excessive acne Androgenic alopecia or hirsutism (terminal hair in male pattern distribution) and Oligomenorrhea (cycles more than 35 days apart but less than 6months apart) or amenorrhea (absence of menstruation for 6-12 months after a cyclic pattern has been established).
Exclusion criteria
Exclusion criteria: Women with BMI =25 Age=35 years Smoker Women with active liver disease Women with known coagulation disorders Undiagnosed vaginal bleeding Women who took OCP in preceding 3months Amenorrhea for=1year Women with secondary causes of hyperandrogenism like Cushing syndrome, late onset Congenital adrenal hyperplasia, gross hypothyroidism and hyperprolactinemia
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Proportion of users with TC/HDL and LDL discordance Timepoint: 12 months | — |
Secondary
| Measure | Time frame |
|---|---|
| LDL/HDL ratio, HOMA-IR and Free Testosterone level , sFG score Timepoint: 6month and one year | — |
Countries
India
Contacts
Public ContactSubhankar Dasgupta
Chittaranjan Seva Sadan and Sishu Sadan, College of Obstetrics Gynaecology and Child Health
Outcome results
None listed