Comparison of Xylitol and fluoride toothpaste and their effect on plaque, salivary pH and Streptococcus mutans

â??To assess and compare the effectiveness of commercially available 25% xylitol and 1000 ppm fluoride toothpastes on salivary pH, plaque and Streptococcus mutans count among 12-16 year old childrenâ?? - A clinical trial.

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2018/02/011866

Enrollment

Registered

2018-02-13

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Intervention1: 25% xylitol toothpaste: Ingredients include Water, xylitol (25%), hydrated silica, glycerin, sorbitol, sodium bicarbonate, sodium carbonate, sodium coco-sulfate, carrageenan (Chondrus c

Eligibility

Inclusion criteria

Inclusion criteria: Study subjects in the age group of 12-16 years. Study subjects with fully erupted permanent teeth. Residential homes that gave permission to conduct the study. Study subjects staying in those residential homes willing to give assent to participate in the study.

Exclusion criteria

Exclusion criteria: Study subjects with any systemic disease. Study subjects with history of taking antibiotics three months prior or during the course of the study. Any medically compromised study subjects. Subjects undergoing orthodontic therapy. Study subjects exposed to professionally applied topical fluorides.

Design outcomes

Primary

Measure	Time frame
25% xylitol toothpaste was as effective as the conventional 1000 ppm fluoridated toothpaste in the control of plaque, Streptococcus mutans count and salivary pH levels.Timepoint: Time intervals of 30 days Salivary pH, plaque scores and Streptococcus mutans count	—

Secondary

Measure	Time frame
Follow-up for measuring stretptococcus mutans count, plaque scores and salivary pH levels.Timepoint: 60 days and 90 days	—

Countries

India

Contacts

Public ContactShruti Ramesh

Bangalore Institute of Dental Sciences

vansan25@gmail.com9880030208

Outcome results