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Effect of sedative drugs during breathing after surgery

Comparison of sedation efficacy of intravenous infusion of Dexmedetomidine vs propofol in patients requiring postoperative mechanical ventilation after head and neck cancer surgeries -A randomized prospectivestudy

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2018/02/011863
Enrollment
80
Registered
2018-02-12
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- Postoperative patients after surgery for Head and Neck Cancers

Interventions

Intervention1: Group II (Dexmedetomidine group): Patients will receive aloading dose of dexmedetomidine 1 mcg/kg over 15 minutes followed by maintenance dose of 0.4µg/kg/hr. The infusion rate will be

Sponsors

AIIMS
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Age > 18 years of age American Society of Anaesthesiologists (ASA) physical status I-III

Exclusion criteria

Exclusion criteria: Patients requiring inotropes Patients allergic to dexmedetomidine or propofol Patients with bradycardia(baseline heart rate Patients who could not be extubated within 24 hours

Design outcomes

Primary

MeasureTime frame
Postoperatively total fentanyl consumption till extubationTimepoint: 24 hours—

Secondary

MeasureTime frame
Duration of mechanical ventilation Extubation time Patients satisfaction Length of ICU stay Length of hospital stayTimepoint: 24 hours, within a week—

Countries

India

Contacts

Public ContactDr Rakesh Garg

AIIMS, New Delhi

drrgarg@hotmail.com9810394950

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026