Health Condition 1: K40- Inguinal hernia Health Condition 2: null- operative patient Health Condition 3: K409- Unilateral inguinal hernia, without obstruction or gangrene Health Condition 4: K409- Unilateral inguinal hernia, without obstruction or gangrene
Conditions
Interventions
Intervention1: Group -K: will receive a sub-anesthetic dose of ketamine (0.3mg/kg) along with GA
Control Intervention1: Group C: will be given 1 ml/kg of 0.125% bupivacaine through the caudal route
Sponsors
All India Institute of Medical Science Bhubaneswar
Eligibility
Inclusion criteria
Inclusion criteria: children below 6yr and above 2 month posted for elective inguinoscrotal or lower limb surgery
Exclusion criteria
Exclusion criteria: children with contraindication to caudal anesthesia, or those with cardiovascular diseases, anaemia, known drug allergy to ketamine or bupivacaine, children with clotting disorders, or those whose parents/guardians refuse to provide consent
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To identify, the efficacy of sub-anesthetic dose of ketamine (0.30 mg/kg) compared to caudal bupivacaine (0.125%, 1ml/kg) for post op analgesia in pediatric patient. The response to pain is defined as FLACC score less than or equal to four immediately after surgery. The primary outcome of this study is to measure the proportion of patients achieving the response in each group. Timepoint: post operative | — |
Secondary
| Measure | Time frame |
|---|---|
| Difference in inflammatory markers (IL6 and TNF Ã?±) between two groups. - intra operative analgesic requirement time to extubation, difference in PONV, difference in sedation scores, incidence of emergence delirium Timepoint: 1 yr | — |
Countries
India
Contacts
Public ContactDr Alok Kumar Sahoo
All India Institute of Medical Science, Bhubaneswar.
Outcome results
None listed