Health Condition 1: C148- Malignant neoplasm of overlappingsites of lip, oral cavity and pharynx Health Condition 2: null- Patients who are undergoing Head & Neck Radiotheraphy for cancer
Conditions
Interventions
Intervention1: Probiotics: A blend of Probiotics powder will be compared to standard antifungal agent(Candid mouth paint)
Control Intervention1: Standard antifungal agent(Candid mouth paint): candid m
Sponsors
DrRadhika D
Eligibility
Inclusion criteria
Inclusion criteria: individuals who underwent head & neck radiotherapy with dosage of 2 Grays/day in a tertiary care center, who were clinically healthy and had not used antibiotics for the previous 3 months will be selected.
Exclusion criteria
Exclusion criteria: Patients with emergency conditions were not included and will be treated immediately. If any new fact that could influence the results (e.g.: antibiotics use) emerged during the course of the study, the samples of that patient will also excluded
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Difference in Candida CFU counts i.e. before vs after probiotic therapy will be considered as an outcome measure.Timepoint: Initial salivary Candida CFU counts before intervention and another salivary Candida CFU counts within three days after 30 days intervention period. | — |
Secondary
| Measure | Time frame |
|---|---|
| NoneTimepoint: 0 | — |
Countries
India
Contacts
Public ContactDr Radhika Doppalapudi
Drs. Sudha and Nageswararao Siddhartha Institute of Dental Sciences
Outcome results
None listed