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Effect of closure of defect in the heart on lungs in patients with left to right shunt and right to left shunt

Assessment of pulmonary mechanics and gas exchange in patients with cyanotic and acyanotic congenital heart disease before and after surgical repair

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2018/02/011773
Enrollment
100
Registered
2018-02-08
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- Children having cyanotic or acyanotic congenital heart disease will be included in the study

Interventions

Intervention1: Patient with acyanotic heart disease after cardiopulmonary bypass: After coming Off cardiopulmonary bypass Saturation, End tidal carbon di oxide, Central venous pressure, Peak and Plate

Sponsors

Lokmanya Tilak municipal medical college and Hospital
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients in the above age group with cyanotic and acyanotic heart disease undergoing intracardiac repair will be included in this study

Exclusion criteria

Exclusion criteria: Pre existing pulmonary oedema complex congenital heart disease

Design outcomes

Primary

MeasureTime frame
Change in the Peak airway pressure Change in the Plateau airway pressure Change in the pulmonary artery pressure Change in the dynamic and static compliance of lung Change in the pulmonary artery pressure Timepoint: Changes will be noted 5 minutes after coming off pump and then 10 minutes of giving Protamine—

Secondary

MeasureTime frame
Effect of cardiopulmonary bypass time and on pump heamatocriton Static compliance of the lungTimepoint: 10 minutes after coming off pump—

Countries

India

Contacts

Public ContactDr Nivedita H Dhankute

Lokmanya Tilak Municipal Medical College and General Hospital

nivedita.dhankute8@gmail.com9096617044

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026