Use of dexamethasone for middle thigh block in patients of knee ligament surgeries and its effect on requirement of postoperative pain relieving medicines.

Morphine sparing effect of dexamethasone as an adjuvant to ropivacaine in ultrasound guided adductor canal block following arthroscopic anterior cruciate ligament reconstruction surgery.

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2018/02/011771

Enrollment

Registered

2018-02-08

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- Patients undergoing knee ligament reconstruction surgeries

Interventions

Intervention1: Group I- Patients will receive adductor canal block (ACB) with 16 ml of a solution ( 15 ml of 0.5% ropivacaine plus 1 ml of sterile normal saline to make a final volume of 16 ml) and 5

Eligibility

Inclusion criteria

Inclusion criteria: 1. ASA physical status I and II of either sex. 2. Age between 18 to 60 years 3. BMI >20 to 4. Scheduled for ACL reconstruction surgery.

Exclusion criteria

Exclusion criteria: 1. Patients having history of substance abuse. 2. Patients with coagulopathy and bleeding disorders. 3. Preexisting peripheral neuropathy. 4. Preexisting local infection at the site of block. 5. Pregnant and lactating women. 6. Inability to understand functioning of PCA pump and VAS (VisualAnalogue Scale). 7. Contraindication to study drugs ropivacaine, dexamethasone and morphine. 8. Patients having haemodynamic instability, hypotension,bradycardia, hepatic dysfunction. 9. Patients on regular chronic pain management drugs for the last three months.

Design outcomes

Primary

Measure	Time frame
To study morphine sparing effect of dexamethasone as adjuvant to ropivacaine in ultrasound guided ACB following arthroscopic ACL reconstruction surgery.Timepoint: To study cumulative morphine consumption at 24 hours. Morphine consumption will be monitored at 0,2,4,6,8,12 and 24 hours interval.	—

Secondary

Measure	Time frame
To study postoperative pain relief,haemodynamics and adverse effects after ultrasound guided ACB following arthroscopic ACL reconstruction surgery.Timepoint: Preoperatively (baseline),immediately after block 0, 5, 10, 15, 20, 30, 60 minutes and followed by 2, 4, 6, 8, 12 and 24 hours interval.	—

Countries

India

Contacts

Public ContactDr Deepak Thapa

Govt Medical College And Hospital

drpallavisingh2015@gmail.com9953365714

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026