Skip to content

A clinical trial to study effect of two drugs lignocaine alone and in combination with dexamethasone on prpofol injection pain

Comparative study of effect of intravenous lignocaine versus intravenous lignocaine and dexamethasone combination pretreatment on propofol injection pain

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2018/02/011747
Enrollment
80
Registered
2018-02-07
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical Health Condition 2: null- Propofol injection pain

Interventions

Intervention1: Intravenous injection of lignocaine, lignocaine and dexamethasone combination before propofol induction: pain after propofol injection will be evaluated. Control Intervention1: lignocai

Sponsors

Dr Chetna Umrigar
Lead Sponsor
DrSmita R Engineer
Collaborator

Eligibility

Inclusion criteria

Inclusion criteria: ASA status I, II Patients who required general anaesthesia

Exclusion criteria

Exclusion criteria: 1.ASA status III, IV, V 2.Hypersensitivity reaction to study drug, soyabean oil, glycerol, egg lecithin 3.Pregnant or lactating patients 4.Patients with history of chronic pain with neurologic, psychiatric, cardiac, renal or liver disease or taking sedative or analgesic preoperatively

Design outcomes

Primary

MeasureTime frame
(1) Withdrawal response score(2) Verbal rating score (3) Behavioral signsTimepoint: Pain intensity will be evaluated during 10 second pause up to 120seconds before induction of anaesthesia

Secondary

MeasureTime frame
pulse, NIBP, SP02, ECGTimepoint: Hemodynamic data will be recorded as basal ,after premedication ,pulse and spo2 at every 10 seconds interval for 60 seconds after injecting study drug ,after releasing cuff ,induction and every 5 minutes for 20 min.;Subjects will be contacted for 24â??h following surgery and questioned about pain, edema, wheal, flare response or swelling at the injection site.Timepoint: 24 hours after surgery

Countries

India

Contacts

Public ContactDr Chetna Umrigar

B.J.Medical college

seng_90@yahoo.com9825504948

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026