Health Condition 1: C509- Malignant neoplasm of breast of unspecified site Health Condition 2: null- Patients suffering from carcinoma breast scheduled to undergo modified radical mastectomy (MRM), with ASA status 1-2.
Conditions
Interventions
Intervention1: Serratus Anterior Muscle block with the adjuvant (dexmedetomidine): Interventional group to receive serrates anterior muscle block with local anaesthetic (0.25% ropicvacaine) 18 ml alon
Sponsors
Government Medical College and Hospital Chandigarh
Eligibility
Inclusion criteria
Inclusion criteria: Inclusion criteria: 1. Females diagnosed with carcinoma breast. 2. American Society of Anesthesiologists physical status I-II 3. Age 18-80 years.
Exclusion criteria
Exclusion criteria: Exclusion criteria: 1. History of relevant drug allergy. 2. History of psychiatric illness, substance abuse. 3. Severe cardiovascular, respiratory, liver diseases, metabolic or neurological disease. 4. Chronic treatment with analgesics. • Pregnancy. • Coagulopathy. • Infection at planned injection site. • Psychological inability of the patient to understand visual analogue scale.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To calculate and compare cumulative morphine consumption over 24 hours in patients receiving serratus anterior muscle block with and without dexmedetomidine.Timepoint: Patient will be monitored for haemodynamic variables and these recordings will be assessed at 30mins, 1hr, 4hrs, 8hrs, 12hrs and 24hrs. Simultaneously, at these time intervals the pain will also be assessed using VAS score which will be evaluated both at rest and on movement. | — |
Secondary
| Measure | Time frame |
|---|---|
| To monitor and compare reduction in pain intensity, to compare the dose of total anti emetics, to monitor haemodynamic variables and to note side effects of the procedure/drugs in use all for 24hrs.Timepoint: Patient monitored for haemodynamic variables along with pain at rest and on movement, assessed at 30mins, 1hr, 4hr, 8hr, 12hr, 24hr | — |
Countries
India
Contacts
Public ContactDr Satinder Gombar
Government Medical College and Hospital, Chandigarh
Outcome results
None listed