A clinical trial to study effect of Allogenic human pulp derived mesenchymal stem cells in patients with intrabony defects

Comparative evaluation of Beta-tricalcium phosphate with or without Allogenic human pulp derived mesenchymal stem cells in the treatment of human intrabony defects

Status

Active, not recruiting

Phases

Phase 1Phase 2

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2018/02/011734

Enrollment

Registered

2018-02-06

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Intervention1: Allogenic human pulp derived mesenchymal stem cells (AHPDMSCs) with Beta-tricalcium phosphate bone graft: This is a interventional trial to evaluate the efficacy of Allogenic human pul

Eligibility

Inclusion criteria

Inclusion criteria: 1) Systemically healthy patients with diagnosed to have chronic periodontitis with atleast one intrabony defect with defect depth >= 3mm 2) probing depth >= 5mm

Exclusion criteria

Exclusion criteria: 1)Patients having systemic diseases 2)History of antibiotics use in the past 6 months 3)Previous periodontal surgeries within 1 year on study tooth 4)Pregnant and lactating mothers Smokers

Design outcomes

Primary

Measure	Time frame
Increase in linear bone growth and % bone fillTimepoint: baseline and 6 months	—

Secondary

Measure	Time frame
clinical attachment level gain and probing depth reductionTimepoint: baseline and 6 months	—

Countries

India

Contacts

Public ContactDr Harini Mitta

Sri Sai College of Dental Surgery Vikarabad

drkrishreddy@gmail.com9849995613

Outcome results