Health Condition 1: null- Adult non-diabetic patients of either sex aged between 18 and 65 years with proven or clinically suspicious peritonitis undergoing emergency laparotomy
Conditions
Interventions
None listed
Sponsors
Dr Souvik Maitra
Eligibility
Inclusion criteria
Inclusion criteria: Adult non-diabetic patients of either sex aged between 18 and 65 years with proven or clinically suspicious peritonitis undergoing emergency laparotomy. Clinically proven peritonitis defined as ascitic fluid culture positive for organisms OR asciá¹ic fluid PMN counts more than 250cells per mm3 or intraabdominal surgically identifiable primary source of infection. Clinically suspected peritonitis is defined as Abdominal muscle guarding or rigidity and signs of sepsis including fever or hypothermia, hypotension, tachycardia or SOFA score positive.
Exclusion criteria
Exclusion criteria: 1. Patients or relativeâ??s refusal to consent for study 2. History of previous exploratory laparotomy in the current hospitalization period 3. History of ICU stay in last 6months 4. Pre-existing significant cardiac, renal and hepatic diseases 5. Intraoperative massive blood loss or massive transfusion
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| in-hospital mortalityTimepoint: During hospital stay | — |
Secondary
| Measure | Time frame |
|---|---|
| Length of ICU stayTimepoint: During ICU stay;Length of stay in hospitalTimepoint: During hospital stay;Need for renal replacement therapy (RRT)Timepoint: During ICU stay;New onset acute renal injury as per KDIGO criteriaTimepoint: During ICU stay;Requirement of mechanical ventilation (number of days on mechanical ventilation)Timepoint: During ICU stay ;Requirement of total parenteral nutrition (number of days on TPN)Timepoint: During hospital stay;Requirement of vasopressor support (number of days on vasopressor)Timepoint: During ICU stay | — |
Countries
India
Contacts
Public ContactDr Souvik Maitra
All India Institute of Medical Sciences, New Delhi
Outcome results
None listed