Comparison between ondansetron and gabapentin for prevention of vomiting after operation.

A comparative study between ondansetron and gabapentin for prevention of postoperative nausea and vomiting following maxillofacial surgery

Status

Active, not recruiting

Phases

Phase 3Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2018/02/011683

Enrollment

Registered

2018-02-05

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- American Society of Anesthesiologists Physical Status I and II

Interventions

Intervention1: Gabapentin U.S.P. 300mg: Single dose Gabapentin tablet will be administered orally with sips of water one hour before induction of anaesthesia. Control Intervention1: Ondansetron Hydroc

Eligibility

Inclusion criteria

Inclusion criteria: 1.Patients of ASA physical status I and II 2.Patients willing to participate 3.Patients scheduled to undergo maxillofacial surgery in whom antiemetic is indicated.

Exclusion criteria

Exclusion criteria: 1. Patient refusal to participate. 2. Patient with known sensitivity to ondansetron and gabapentin 3. Patient on concomitant antiemetic medication. 4. Pregnant or lactating female.

Design outcomes

Primary

Measure	Time frame
Incidence of postoperative nausea and vomitingTimepoint: 0-2 hr, 2-24 hr after operation	—

Secondary

Measure	Time frame
Adverse effects like dizziness, headache, drowsiness.Timepoint: 0-2 hr, 2-24 hr after operation	—

Countries

India

Contacts

Public ContactG K Thapaliyal

ITS Dental College Hospital & Research Centre

PREKSHADUBEY@GMAIL.COM9773909218

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026