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The Correlation of Cardiopulmonary Exercise Testing and Severity of Pulmonary Artery Hypertension in Patients with Chronic Obstructive Pulmonary Disease

The correlation of cardiopulmonary exercise testing and severity of pulmonary artery hypertension in patient with chronic obstructive pulmonary disease

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2018/02/011657
Enrollment
29
Registered
2018-02-01
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- COPD with Pulmonary Artery Hypertension

Interventions

Control Intervention1: Cardiopulmonary exercise testing (CPET): 1.Maximum oxygen uptake(VO2 max) 2. VO2 @ AT 3. Oxygen pulse (VO2/ HR) 4. Peak RER 5. Peak VE 6. VD/VT 7. Heart rate recovery (HRR) 8

Sponsors

Jamia Milllia Islamia
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Severe to very severe COPD patients (as per GOLD criteria) with systolic pulmonary artery hypertension (sPAP) >= 30 mm Hg. Ability to perform symptom limited cycle ergometer cardiopulmonary test.

Exclusion criteria

Exclusion criteria: Acute MI (3-5 days) or cardiac disorders Unstable angina History of acute viral myocarditis Syncope Uncontrolled asthma Uncontrolled heart failure Room air desaturation at rest (85%)

Design outcomes

Primary

MeasureTime frame
in cardiopulmonary exercise testing 1.Maximum oxygen uptake(VO2 max) 2.Oxygen pulse (VO2/ HR) 3.VD/VT 4.PETCO2â?¨ 1. Systolic pulmonary artery pressure (sPAP) 2. Right atrial pressure (RAP) Timepoint: one time—

Secondary

MeasureTime frame
In Cardiopulmonary exercise testing (CPET) 1. VO2 @ AT 2.Peak RER 3.Peak VE 4. Heart rate recovery (HRR) 5. VE/VCO2 6.Desaturation (%)Timepoint: one time—

Countries

India

Contacts

Public ContactJamal Ali Moiz

Jamia Millia Islamia

jmoiz@jmi.ac.in1126981717

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026