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A clinical trial to study the outcomes of two intraoperative fluid management strategies to guide fluid therapy in renal transplant recepient patients

Intra-operative fluid management in end stage renal disease patients undergoing renal transplantation: Comparison of Pulse Pressure Variation with Central Venous Pressure

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2018/01/011638
Enrollment
70
Registered
2018-01-31
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: N186- End stage renal disease

Interventions

Intervention1: Pulse Pressure Variation Guided Fluid Management Intraoperatively: Pulse Pressure Variation (PPV) is a dynamic index of fluid responsiveness based on the mechanical ventilation induced

Sponsors

Postgraduate institute of medical education and researchPGIMER Chandigarh
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients with End Stage Renal Disease undergoing Renal Transplantation

Exclusion criteria

Exclusion criteria: Active coronary artery disease or congestive heart failure Atrial fibrillation or flutter Valvular Heart Disease Significant pulmonary insufficiency

Design outcomes

Primary

MeasureTime frame
To determine the ability of Pulse Pressure Variation guided fluid therapy as an alternative to CVP guided fluid therapy in renal transplant recipients by comparing the amount of fluid administered at the end of surgeryTimepoint: 1 hour post op—

Secondary

MeasureTime frame
To compare adequacy of tissue perfusion at the end of surgery.To find out the total volume of fluid administered in two groups during surgery and in the immediate post-operative period Timepoint: day 1 post surgery—

Countries

India

Contacts

Public ContactKamal Kajal

Postgraduate institute of medical education and research, Chandigarh

kamal.kajal@gmail.com9560412726

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 20, 2026