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Optimizing the Radiotherapy plan according to tumor shrinkage in Head and Neck Cancers-A Prilimenary Study

Adaptive Radiotherapy in Head and Neck Cancers-A Prospective Study

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2018/01/011637
Enrollment
30
Registered
2018-01-31
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- Head and Neck Cancer patients who will be suitable for Radical Chemo-radiotherapy will be recruited for this study

Interventions

Intervention1: ART arm: Adaptive radiotherapy for locally advanced head and neck cancers Control Intervention1: NA: NA

Sponsors

CSIR
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Age > 18 years Histologically proven squamous cell carcinoma Written informed consent Locally advanced head and neck cancers

Exclusion criteria

Exclusion criteria: 1.Resection of primary tumor 2.Delivery of induction chemotherapy prio to radiation 3.Prior history of malignancy 4.History of prior radiation 5.KPS

Design outcomes

Primary

MeasureTime frame
Primary outcome To evaluate the dosimetric changes in PTV and organs at risk during adaptive radiotherapy. 2.To assess acute and chronic toxicities of treatment. Secondary Outcome To assess local control and survival Timepoint: weekly during treatment then at 1 month, 3 monthly for 2 years and 6 monthly for 5 years—

Secondary

MeasureTime frame
To assess local control and survival Timepoint: every 3 monthly for local control for 2 years and then 6 monthly for 5 years and survival at 3 and 5 years;To assess local control and survival Timepoint: every 3 monthly for local control for 2 years and then 6 monthly for 5 years and survival at 3 and 5 years—

Countries

India

Contacts

Public ContactDr Suman Bhasker

All India Institute of Medical Sciences,New Delhi

drsumanbhasker@gmail.com9811093418

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026