Health Condition 1: null- chronic kidney disease patient
Conditions
Interventions
Intervention1: Bedtime group: Antihypertensive Dose as per physician discretion to control Blood Pressure
Addition of antihypertensive in night time only
Oral route only
Duration of therapy is 1 yea
Sponsors
IPGMER snd SSKM Hospital
Eligibility
Inclusion criteria
Inclusion criteria: 1. MDRD eGFR 2. Patients of either sex who were 18 years of age or older are eligible. 3. Patients on antihypertensives taking >= 1 drug(s) of which at least 1 dose is being taken in morning or afternoon 4. Patients should be ambulatory
Exclusion criteria
Exclusion criteria: 1. Suspicion of secondary hypertension, other than CKD. 2. Recent stroke (occurring within the previous 3 months). 3. Recent acute myocardial infarction. 4. Recent hospitalization for heart failure 5. Recent revascularization or planned cardiovascular intervention 6. MDRD eGFR 7. Uncontrolled Hypertension (systolic BP >150 mmHg or diastolic BP >90mmHg) 8. Pregnancy 9. Atrial fibrillation Refusal to undergo repeated follow up visits and ambulatory blood pressure monitoring.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1. Conversion to dipper pattern from non dipper in two groups 2. Rate of fall of eGFR in two groups 3. Change in cardiac structure like LV Mass Index and LV ejection fractionTimepoint: Conversion to dipper from non dipper at 3 months Change in eGFR and Cardiac structure at 1 year | — |
Secondary
| Measure | Time frame |
|---|---|
| Changes in 24 hour proteinuriaTimepoint: 1 year | — |
Countries
India
Contacts
Public ContactVaibhav Tiwari
IPGMER
Outcome results
None listed