Health Condition 1: null- (22 oral cancer, 22 potentially malignant lesions, 22 tobacco users and 22 controls)
Conditions
Interventions
None listed
Sponsors
Manipal College of Dental Sciences
Eligibility
Inclusion criteria
Inclusion criteria: Oral cancer group: Histopathologically confirmed cases of Oral cancer and who were above 18 years of age would be included. Potentially malignant lesions group: Histopathologically confirmed cases of potentially malignant lesions (leukoplakia, oral sub-mucous fibrosis) and who were above 18 years of age would be included. Tobacco users group: Known habitual tobacco users (of more than 1 year smoking or smokeless tobacco) and who were above 18 years of age would be included. Control groups: Healthy individuals, without the habit of tobacco, with no gross pathologies and who were above 18 years of age would be included.
Exclusion criteria
Exclusion criteria: Patients with systemic disease, patient had a history of prior malignancy, immunodeficiency, other autoimmune disorders, hepatitis, or human immunodeficiency virus infection; and prior treatment in the form of chemotherapy, radiotherapy, surgery or alternative medicine, pregnancy or lactation
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Salivary MMP - 9Timepoint: Baseline (immediately) | — |
Secondary
| Measure | Time frame |
|---|---|
| NATimepoint: NA | — |
Countries
India
Contacts
Public ContactGadicherla Srikanth
Manipal College of Dental Sciences,
Outcome results
None listed