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Effect of mannitol in lowering intra cranial tension during robotic assisted procedures in head down position

Effects of different doses of mannitol on intracranial pressures during robotic assisted procedures in tredelenberg position. A single center randomized control trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2018/01/011556
Enrollment
60
Registered
2018-01-24
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- urological diseases, gynaecological diseases

Interventions

Intervention1: Mannitol at the dose of 0.5g/kg single dose: Mannitol has been well documented as one of the therapies in reducing ICP. Mannitol has been used in different doses in controlling rise in

Sponsors

POSTGRADUATE INSTITUTE OF MEDICAL EDUCATION AND RESEARCH CHANDIGARH
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Age above18 years 2. ASA class I-III 3. Urological patients undergoing robotic assisted surgeries 4. Gastrointestinal patients undergoing robotic assisted surgeries 5. Gynecological patients undergoing robotic assisted surgeries

Exclusion criteria

Exclusion criteria: 1. ASA class IV and above 2. Patients with a history of glaucoma. 3. Patients with corneal disease, retinal vascular disease 4. Patients with known cerebrovascular disease 5. Patients with known renal disease 6. Patient not giving consent 7. Patient having known allergy to any drug. 8. Pregnant patients

Design outcomes

Primary

MeasureTime frame
To find out the effects of using different doses of mannitol on ICP in patients undergoing robotic assisted abdominal surgery in steep Tredelendburg position.Timepoint: T1 before surgery in supine position after induction(10 mins postracheal Intubation) â?¢ T2 After Tredelendburg position â?¢ T4,5,6â?¦ every 30 mins â?¢ Tdedock After dedocking â?¢ Tsupine After patient is made supine

Secondary

MeasureTime frame
To find out the effects of the following factors in managing the rise in ICP and facial edema (i) Duration of surgery (ii) Total I.V. fluid infused during surgery Timepoint: End of surgery

Countries

India

Contacts

Public ContactDr Kamal Kajal

MD,PDCC

kamal.kajal@gmail.com1722756500

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026