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Role of Doxycycline in the treatment of Dengue infection in Children

Role of Doxycycline in Management of Children with Dengue Infection

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2018/01/011548
Enrollment
202
Registered
2018-01-24
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- Dengue Infection

Interventions

Intervention1: Doxycycline: oral Doxycycline at a dose of 5mg/kg twice a day for 7 days Control Intervention1: Placebo: Salt without active ingredient which looks similar to the drug

Sponsors

Dr Ashok H C
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: children between 8yrs and 18yrs with confirmed dengue fever

Exclusion criteria

Exclusion criteria: children in whom oral medications are contraindicated children with known hypersensitivity to Doxycycline Children on antiepileptic drugs children who have recieved doxycycline elsewhere for present illness

Design outcomes

Primary

MeasureTime frame
DeathTimepoint: with in 7 days or discharge from hospital which ever later

Secondary

MeasureTime frame
Admission to hospital, IV fluid requirement, ICU admission, Need for transfusion, Progression of disease from dengue fever to DF with warning signs to Severe DengueTimepoint: 7 days from intervention

Countries

India

Contacts

Public ContactAshok H C

JSS HOSPITAL AND MEDICAL COLLEGE

vghunsur@rediffmail.com

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026