Health Condition 1: null- Adult patients undergoing hepatic resections(2 segments) Health Condition 2: D134- Benign neoplasm of liver Health Condition 3: C23- Malignant neoplasm of gallbladder Health Condition 4: C22- Malignant neoplasm of liver and intrahepatic bile ducts
Conditions
Interventions
Intervention1: To guide fluid therapy in hepatic resections, using Pulse Pressure Variation: Pulse Pressure Variation is a dynamic indicator of fluid responsiveness as compared o the conventional low
Sponsors
PGIMER
Eligibility
Inclusion criteria
Inclusion criteria: All adult patients scheduled for open, elective hepatic resection (>= 2 segments). The group will also include patients who are initially approached laparoscopically but converted to an open resection. Patients undergoing additional procedures will also be assessed for eligibility.
Exclusion criteria
Exclusion criteria: Active coronary artery disease or congestive heart failure, Atrial fibrillation or flutter, Acute renal dysfunction, severe portal hypertension, Pregnancy, Extreme Body mass index (BMI) >45 OR
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| â?¢ To compare Pressure Variation(PPV) as an alternative to Low Central Venous Pressure(LCVP) guided approach in order to reduce blood loss during hepatic resectionsTimepoint: 30th July 2018 | — |
Secondary
| Measure | Time frame |
|---|---|
| â?¢ To compare arterial lactate levels during different phases of liver resection. Timepoint: 1 day post operatively | — |
Countries
India
Contacts
Public ContactDr Kamal Kajal
Post graduate Institiute of Medical Education and Research(PGIMER)
Outcome results
None listed