Health Condition 1: null- Newly diagnosed (less than 2 years) patients of Rheumatoid Arthritis
Conditions
Interventions
Intervention1: Vitamin D3 and calcium: 60,000 IU 1, 25 dihydroxy vitamin D3 + calcium (1000 mg/day)
Control Intervention1: Calcium: oral calcium (1000 mg/day)
Control Intervention2: Calcium: oral calc
Sponsors
Dr Dibyendu Mukherjee
Eligibility
Inclusion criteria
Inclusion criteria: Newly diagnosed Rheumatoid Arthritis (duration less than 2years) subjects, who have not been treated with any medication other than analgesics prior to study recruitment.
Exclusion criteria
Exclusion criteria: (i) patients who have been on steroids during the past year; (ii) known to have disorders of calcium metabolism such as malabsorption, hyperparathyroidism, chronic renal failure, renal tubular acidosis or pancreatitis; (iii) known allergy to DMARDs, 1,25 dihydroxy vitamin D3 or calcium; (iv) patients unlikely for follow-up in the following 8 weeks; (v) patients unable to afford triple DMARD therapy; (vi) patients who were suspected to have vasculitis; (vii) and patients unable to mark the pain scale.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Minimum time (days) required for onset of pain relief (Tm)Timepoint: From study onset to end of 2 months | — |
Secondary
| Measure | Time frame |
|---|---|
| %change in visual analogue score (VAS) score from baseline.Timepoint: From study onset to end of 2 months | — |
Countries
India
Contacts
Public ContactDibyendu Mukherjee
KPC Medical College & Hospital
Outcome results
None listed