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A low dose of ketamine as continuous infusion for prevention of shivering under spinal anaesthesia.

Prophylactic Low Dose Ketamine Infusion For Prevention Of Shivering During Spinal Anaesthesia- A Randomised Double blind Clinical Trial.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2018/01/011530
Enrollment
60
Registered
2018-01-24
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical Health Condition 2: null- Patients posted for any abdominal, gynecological, lower limb surgeries under spinal anaesthesia.

Interventions

Intervention1: Inj Ketamine: single Low dose ketamine bolus 0.2mg/kg will be administered iv before giving spinal anaesthesiaa followed by infusion of ketamine 0.1 ml/kg/hr iv throughout the period of

Sponsors

Dr Ramyavel T
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: All patients of age group 18 to 60 years of ASA 1 and 2 undergoing abdominal and lower limb surgeries under spinal anaesthesia.

Exclusion criteria

Exclusion criteria: 1) Any contraindication or un willingness for spinal anaesthesia. 2) Patients with BMI > 30 kg/m2 3) Patients with uncontrolled hypertension, risk of coronary or vascular disease. 4) Increased intraocular or intracranial pressure/glaucoma. 5) History of psychosis, convulsions, neuromuscular diseases. 6) Patients with hepatic or renal dysfunction

Design outcomes

Primary

MeasureTime frame
Incidence of intraoperative shivering.Timepoint: Grade of shivering intraoperatively will be assessed and recorded every 5 min for the initial 30 min followed by every 15 min till the end of surgery.

Secondary

MeasureTime frame
Degree of sedationTimepoint: Assessed and recorded every 5 min for the initial 30 min followed by every 15 min till the end of surgery and also for 2 hours post operatively.;Hemodynamics ((MAP, HR, RR, temperature and SPo2)Timepoint: will be assessed and recorded every 5 min for initial 30 min followed by every 15 min till the end of surgery.;Incidence of Post operative shivering.Timepoint: Grade of shivering assessed every 30 min for 2 hours postoperatively.

Countries

India

Contacts

Public ContactDr Ramyavel T

Pondicherry Institute of Medical Sciences - A unit of Madras Medical Mission

ramyavel1988@gmail.com9487630425

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026