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Effectiveness of Intra-operative nerve block(PECS-II) with continuous infusion of local anaesthetic drug compared to single dose infiltration of same drug at the end of surgery.

"Efficacy of Pectoralis (PECS-II) nerve block versus Bupivacaine Wound infiltration in the Management of Pain relief Following Modified Radical Mastectomy" a Randomised Controlled Trial.

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2018/01/011523
Enrollment
76
Registered
2018-01-23
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- Patient between 18-65 years of age. No previous Drug allergy. Non-pregnant/non-lactating women. No previous Radiation exposure. No previous surgery. No previous history of CA Breast.

Interventions

Intervention1: GROUP- P2: Patients undergoing PECS-II block Control Intervention1: GROUP- WI: Patients undergoing Wound Infiltration Technique

Sponsors

Jawaharlal Institute Of Post Graduate Medical Education and Research JIPMER
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1.All operable Breast Cancer patients planned for Modified Radical Mastectomy under General Anaesthesia in the department of General Surgery( Undergoing in JIPMER).

Exclusion criteria

Exclusion criteria: 1.Patients with age 65 years 2.Patients with history of drug allergy 3.Pregnant and lactating patients 4.Previous Breast irradiation 5.Recurrent Breast Cancer

Design outcomes

Primary

MeasureTime frame
1. Intra-operative use of PECS-II block by securing catheter in place in MRM patients, will reduce post-operative pain more significantly resulting in less usage of Opioids thus reducing their side effects and they might also reduce incidence of chronic pain following Mastectomy.Timepoint: within 2 days.

Secondary

MeasureTime frame
Reduced Post-operative nausea and vomiting due to less opioid consumption. assess satisfaction during discharge.Timepoint: for initial 48 hours. Then at the time of discharge.

Countries

India

Contacts

Public ContactDr Balamourougan K

Jawaharlal Institutue Of Post graduate Medical Education and Research

drbalak@gmail.com9443617089

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026