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Anti-Diabetes Drug response study

Evaluation of the impact of allele specific gene expression on therapeutic response to oral hypoglycemic drugs in type 2 diabetes - AGED

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2018/01/011508
Enrollment
450
Registered
2018-01-23
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- Type 2 Diabetes

Interventions

Control Intervention1: Not Applicable: Not Aplicable

Sponsors

Science and Engineering Research Board SERB
Lead Sponsor
Dr K Satyamoorthy
Collaborator
Dr Sanjiban Chakrabarty
Collaborator
Dr Shashikiran Umakanth
Collaborator
Dr Shivashankara KN
Collaborator
Mr Manik Vohra
Collaborator

Eligibility

Inclusion criteria

Inclusion criteria: Clinically diagnosed drug naïve T2D patients (based on world health organization criteria)

Exclusion criteria

Exclusion criteria: Patients allergic to anti hyperglycemic drugs, type 1 diabetes mellitus, maturity onset diabetes of young (MODYs), gestational diabetes mellitus and secondary diabetes (e.g. pancreatitis, hemochromatosis), clinical renal or hepatic impairment, Cardiac problems (myocardial infarction, unstable angina pectoris), uncontrolled hypertension, non ketotic hyperosmolar coma or chronic diabetic complications, use of medications that could alter glucose metabolism, malignant diseases, hematological diseases, infected with hepatitis virus, psychosis, significant digestion, autoimmune diseases and resorption disturbances acute cerebrovascular accidents within the last 6 months will be excluded from the study.

Design outcomes

Primary

MeasureTime frame
The optimization of therapeutic strategy and the potential to expand to patient care.Timepoint: 3 years

Secondary

MeasureTime frame
Better diagnoses, screening and management of diabetic patients in order to achieve individual care should benefit public healthTimepoint: After 3 years

Countries

India

Contacts

Public ContactDr Saadi Abdul Vahab

School of Life Sciences, Manipal University

padmalatha.rai@manipal.edu9448215768

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026