A clinical research to evaluate the effect of sugar free chewing gum containing CPP-ACP (a milk protein with calcium and phosphate) in prevention of white spots (initial stage of dental caries) in patients wearing braces (clip)

Efficacy of sugar free chewing gum containing casein phosphopeptide amorphous calcium phosphate (CPP-ACP) on demineralization around fixed orthodontic brackets - An in vivo study

Status

Active, not recruiting

Phases

Phase 2Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2018/01/011495

Enrollment

Registered

2018-01-23

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Intervention1: Sugar free chewing gum containing CPP-ACP : Two pellets thrice daily for one month Intervention2: Sugar free chewing gum without CPP-ACP : Two pellets thrice daily for one month Con

Eligibility

Inclusion criteria

Inclusion criteria: The criteria for including participants were no active caries lesions, normal salivary flow rate (approximately 1.0 mL/min), and buffer capacity (6.7-7.7). Sound Premolars

Exclusion criteria

Exclusion criteria: active carious lesions, periodontal or any other oral pathology Subjects under antibiotics or any medications that could alter the salivary flow, pH & buffering capacity Dental anomaly- eg. enamel hypoplasia , fluorosis. Premolars- Carious/ Restored / Non vital / Fractured. Patient with known milk protein allergy

Design outcomes

Primary

Measure	Time frame
Vickers Hardness measurement of demineralized enamel around orthodontic bracketsTimepoint: one month	—

Secondary

Measure	Time frame
Mean VAS pain score due to chewing gumTimepoint: one week;to identify the number of appliance breakagesTimepoint: one month.	—

Countries

India

Contacts

Public ContactDr Shailaja R

TN Government Dental College

vimalaortho@gmail.com9884417095

Outcome results