A study to compare improvement in pain relief when intravenous lignocaine is used in patients undergoing surgery to remove the gall bladder.

A Randomized control study of the efficacy of intraoperative intravenous lignocaine infusion in improving post operative analgesia in patients with BMI more than 25, undergoing elective laparoscopic cholecystectomy. - PLIC

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2018/01/011486

Enrollment

Registered

2018-01-23

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- Patients posted for laparascopic elective cholecystectomy

Interventions

Intervention1: 2% Lignocaine: Bolus at induction of 2mg/kg IBW and infusion at 2mg/kg till 30 minutes after the surgery. Control Intervention1: Normal Saline (0.9% Sodium Chloride): Equivalent volume

Eligibility

Inclusion criteria

Inclusion criteria: a)Patients undergoing elective cholecystectomy b)BMI >30 c)ASA I and II d)Age >18

Exclusion criteria

Exclusion criteria: a)ASA III and IV b)allergy to local anaesthetic c)Seizure disorder d)Anti-arrhythmic drug intake in the 1 week before surgery e)Renal/Hepatic Insufficiency f)Psychiatric disorders g)Steroid therapy h)Pregnancy i)Conversion to laparotomy

Design outcomes

Primary

Measure	Time frame
Perioperative AnalgesiaTimepoint: Perioperative Analgesia	—

Secondary

Measure	Time frame
Time to DischargeTimepoint: Time to Discharge;time to pass flatus and initiate feedsTimepoint: time to pass flatus and initiate feeds;Ability to do incentive spirometerTimepoint: 10,30,60,90,120 mins after extubation;Hemodynamic ParametersTimepoint: intubation, insufflation, extubation, post extubation every 30 mins for 2 hours;total muscle relaxant usedTimepoint: intraoperatively;total opioids consumedTimepoint: upto 2 hours fter the surgery	—

Measure

Time frame

Time to DischargeTimepoint: Time to Discharge;time to pass flatus and initiate feedsTimepoint: time to pass flatus and initiate feeds;Ability to do incentive spirometerTimepoint: 10,30,60,90,120 mins after extubation;Hemodynamic ParametersTimepoint: intubation, insufflation, extubation, post extubation every 30 mins for 2 hours;total muscle relaxant usedTimepoint: intraoperatively;total opioids consumedTimepoint: upto 2 hours fter the surgery

—

Countries

India

Contacts

Public ContactPraveen Benjamin D

Christian Medical College Vellore

balooswamy@gmail.com7406777127

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026