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A Clinical trial to study the effects of three different doses of Magnesium Sulphate in decreasing Succinylcholine induced fasciculations

Efficacy of Magnesium Sulphate in attenuation of Succinylcholine induced fasciculations- A Dose finding study

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2018/01/011484
Enrollment
90
Registered
2018-01-23
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- Patients posted for surgeries under genera l anesthesia and receiving Succinyl choline

Interventions

Intervention1: Group 2: MgSO4 at 30mg/kg IV diluted in 10ml NS administored over 10 minutes Intervention2: Group 3: MgSO4 at 40mg/kg IV diluted in 10ml NS administored over 10 minutes Control Interven

Sponsors

VIMS Ballari
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients posted to elective surgery under general anesthesia, belonging to ASA I and II

Exclusion criteria

Exclusion criteria: Patient refusal, history of signifcant systemic disordess, preexisting musculo skeletal disorders, allergy to test drugs,already on magnesium therapy, pregnant patients

Design outcomes

Primary

MeasureTime frame
To compare the efficacy of three different pretreatment doses of magnesium sulphate in reducing incidence and severity of succinylcholine induced fasciculations.Timepoint: Observed for 1 minute after administration of succinylcholine—

Secondary

MeasureTime frame
Haemodynamic responses to intubationTimepoint: at 1,3,5 and 10 min after intubation—

Countries

India

Contacts

Public ContactBala Bhaskar S

Vijayanagar Institute of Medical Sciences

yveda90@gmail.com8050203933

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026