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Comparison of effect of lignocaine and fentanyl versus dilitazem and fentanyl on hemodynamic response during intubation.

A comparison of effect of lignocaine and fentanyl versus diltiazem and fentanyl on hemodynamic response during laryngoscopy and intubation : a prospective randomised double blind study

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2018/01/011483
Enrollment
60
Registered
2018-01-23
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Control Intervention1: lignocaine& fentanyl and diltiazem & fentanyl: lignocaine 1.5mg/kg & fentanyl2mcg/kg diltiazem 0.2 mg/kg & fentanyl 2mcg/kg

Sponsors

NIL
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1 .ASA physical status I or II male and female adults. 2. Age group of 18-60 years scheduled for various elective surgical procedures.

Exclusion criteria

Exclusion criteria: Patient who are not willing to undergo in the study. b) Patients with known allergy to anaesthetic or any other drug. Error of c) Patients with atrio-ventricular conduction block, congestive heart failure, cardiac arrythmia, hypertension or other cardiovascular disease and receiving anti hypertensive drugs and phosphodiestrase inhibitors. d) Anticipated difficulty in intubation. e) Severe obesity (BMI >35kg/m²).

Design outcomes

Primary

MeasureTime frame
to compare between intravenous lignocaine 1.5mg/kg plus fentanyl 2mcg/kg versus injection diltiazem 0.2mg/kg plus fentanyl 2mcg/kg on hemodynamic response during laryngoscopy and intubationTimepoint: 1 year—

Secondary

MeasureTime frame
Ditiazem plus fentanyl is better than lignocaine and fentanyl in attenuating hemodynamic response during laryngoscopy and intubation.Timepoint: 3 min—

Countries

India

Contacts

Public ContactSnigdha Singh

R.N.T Medical Colege udaipur

drlalitkumar@hotmail.com9414352823

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026