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Early lung changes on ultrasound in severe pre-eclampsia

INCIDENCE OF INTERSTITIAL ALVEOLAR SYNDROME ON LUNG SONOGRAPHY IN PREECLAMPTIC WOMEN WITH SEVERE FEATURES : A PROSPECTIVE OBSERVATIONAL STUDY - Interstitial Alveolar syndrome , Severe preeclampsia

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2018/01/011473
Enrollment
50
Registered
2018-01-22
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- pre-eclamptic parturients with severe features

Interventions

Intervention1: NIL: nil

Sponsors

PGIMER
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Preeclamptic patients with period of gestation >20 weeks will be assessed for eligibility for enrollment to the study if they show any one of the following features.11 • BP is >=160 mmHg systolic and/or >=110 mmHg diastolic (on 2 occasions at least 4 hours apart, while the patient is on bed rest) after 20 weeks gestation Â¥ New onset BP is >=140mmHg systolic and/or >=90mmHg diastolic (on 2 occasions at least 4 hours apart, while the patient is on bed rest) with any of the following is present: Â¥ Pulmonary features Â¥ Thrombocytopenia, platelets count Â¥ Serum creatinine >=1.1 mg/L or a doubling of the serum creatinine concentration in the absence of other renal disease Â¥ Impaired liver function, elevated blood concentrations of liver transaminases to twice normal concentration Â¥ Cerebral or visual disturbances

Exclusion criteria

Exclusion criteria: ¥ Pregnancy with severe anaemia ¥ Gestational/chronic hypertension ¥ Pregnancy with known cardiac diseases ¥ Those who are not willing to give consent for participating in the study.

Design outcomes

Primary

MeasureTime frame
To assess the ability of bedside lung ultrasound to detect interstitial alveolar syndrome in preeclamptic women with severe features admitted for delivery.Timepoint: at admission, before delivery and within 24 hours after delivery—

Secondary

MeasureTime frame
The secondary objectives will include association ,if any, with 1. Clinical features of acute breathlessness, tachypnea, respiratory compromise 2. Rapidity of rise in blood pressure over preceding week 3. Change in biochemical parameters 4. Any other secondary features having multisystem involvement 5. To correlate echocardiography finding with lung sonography B-lines (To rule out cardiac diseases) Timepoint: during admission period—

Countries

India

Contacts

Public ContactDr Seshagiribabu Yagani

Department of Anesthesia and Intensive Care, PGIMER

kajalteji@gmail.com9915797677

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026